The Light-to-heat Conversion of Gold Nanoshells and Nanorods in Tissues

Abstract

We perform a set of experiments on photo-heating in
tissues containing gold nanoshells (NSs) and nanorods (NRs). The temperature
of tissues were measured with different amounts gold NSs and NRs under
illumination of a continuous diode laser at 808 nm and power density from 20
to 62 W/cm\(^{2}\). The temperature of the tissues injected gold nanoparticles
increased to $66 \pm  4\(^{\circ}\)C for \(2.1 \times 10^{8}\) NSs and  \(73\pm  4\) 
\(^{\circ}\)C for gold \(5.4 \times 10^{9}\) NRs after 10 min exposition at power density
35 W/cm\(^{2}\). The control tissue without gold nanoparticles demonstrated a
significantly lower temperature \(40 \pm  4\) \(^{\circ}\)C in the same time of
illumination. The temperature can be reached up to around 100\(^{\circ}\)C for
tissue with both NSs and NRs at 62 W/cm\(^{2}\) inrradiation for \(7-10\) min.